5-AMINO-1MQ 10mg

5-AMINO-1MQ 10mg
£30.00

(NOT FOR HUMAN CONSUMPTION RESEARCH USE ONLY) 

5-Amino-1MQ – 10mg Via(5-Amino-1-methylquinolinium)

5-Amino-1MQ  is a small molecule compound—often categorised as a peptide in wellness circles—that acts as a selective inhibitor of the enzyme nicotinamide N-methyltransferase (NNMT). It is primarily studied for its potential to reverse obesity, enhance metabolic efficiency, and support longevity. 

 

How It Works

NNMT is an enzyme often overexpressed in fat tissue and aging cells. When NNMT is too active, it depletes the body's stores of nicotinamide, which is a precursor for NAD+. 

  • Boosts NAD+: By blocking NNMT, 5-Amino-1MQ helps preserve nicotinamide, leading to increased cellular levels of NAD+, a coenzyme vital for energy production.
  • Activates SIRT1: Higher NAD+ levels activate SIRT1, often called the "longevity gene," which improves fat oxidation and mitochondrial function.
  • Shrinks Fat Cells: Unlike stimulants, it targets the cellular root of fat storage, encouraging white adipose tissue to shrink and burn fat rather than storing it. 

 

Potential Benefits

Early preclinical research (mostly in animal models) and anecdotal reports suggest several benefits: 

  • Accelerated Fat Loss: Specifically targets stubborn fat and reduces adipocyte (fat cell) size.
  • Muscle Maintenance: Promotes muscle regeneration and helps preserve lean mass during weight loss.
  • Increased Energy: Users often report higher stamina and physical endurance due to improved mitochondrial output.
  • Metabolic Support: May improve insulin sensitivity and lower systemic inflammation. 

 

Administration and Status

  • Oral Form: Unlike many traditional peptides that require injection, 5-Amino-1MQ is typically administered in oral capsule form.
  • Dosage: Typical research doses range from 50 mg to 150 mg per day, often split into multiple doses.
  • FDA Status: As of January 2026, it is not FDA-approved for human use and is classified as a "research chemical".
  • Safety: While animal studies showed a wide safety margin with no major adverse effects, human safety data is currently non-existent. 

 

Reported Side Effects

Reported side effects are generally mild and include: 

  • Difficulty Sleeping: If taken too late in the day, it may impact circadian rhythms due to elevated NAD+.
  • Gastrointestinal Issues: Some users report mild nausea, bloating, or diarrhea.
  • Temporary Fatigue: A small number of users report a brief period of decreased exercise tolerance during the initial acclimation phase.