SELANK 5/10mg

£18.00

(NOT FOR HUMAN CONSUMPTION RESEARCH USE ONLY) 

Selank

is a synthetic heptapeptide (a chain of seven amino acids) derived from the naturally occurring human peptide tuftsin. Developed in Russia, it is primarily studied for its potential to reduce anxiety and enhance cognitive function. 

 

Core Functions and Mechanism

Selank acts as a neuropeptide, primarily influencing the central nervous system through several pathways: 

  • GABAergic Modulation: It acts as a positive allosteric modulator of GABA-A receptors, enhancing the inhibitory signals that calm the nervous system.
  • Neurotransmitter Balance: It influences levels of dopamine, serotonin, and norepinephrine, which are critical for mood and emotional regulation.
  • BDNF Elevation: Selank may increase levels of Brain-Derived Neurotrophic Factor (BDNF), a protein essential for neuron survival and growth.
  • Enkephalin Stabilization: It helps inhibit the enzymes that break down enkephalins, the body's natural stress-countering peptides. 

 

Potential Benefits

Research and anecdotal reports suggest several cognitive and psychological benefits: 

  • Anxiolytic (Anti-Anxiety): Unlike traditional benzodiazepines, Selank is reported to reduce anxiety without causing sedation, memory loss, or dependency.
  • Cognitive Enhancement: It is categorized as a nootropicbecause it may improve focus, learning, and short-term memory formation.
  • Stress Resilience: By regulating the body's stress response, it helps promote a sense of calm during periods of high pressure.
  • Immune Support: Due to its origin from tuftsin, it possesses immunomodulatory properties that may help regulate the immune system. 

 

Regulatory Status and Safety

The legal status of Selank varies significantly by region:

  • Russia/CIS: Approved for the treatment of generalized anxiety disorder and neurasthenia.
  • United States (FDA): Not approved for human medical use. In 2024, the FDA removed Selank from its "Category 2" compounding list, meaning it is currently ineligible for use in personalized compounded treatments.
  • Sporting Use: While not explicitly on the 2025 WADA Prohibited List, it falls under a general category of non-approved substances that can lead to sanctions.
  • Common Side Effects: Generally well-tolerated, though some users report mild nasal irritation (when used as a spray), headaches, or dizziness.